Related haploidentical donors are a better choice than matched unrelated donors: Point

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Related haploidentical donors are a better choice than matched unrelated donors: Counterpoint.

Publisher's Note: This article has a companion Point by Fuchs. Publisher's Note: Join in the discussion of these articles at Blood Advances Community Conversations.

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introduction although renal transplantation from cadaver is common, living donors continue to be an important source of transplanted kidneys. recipients of living-donor kidneys demonstrate improved graft survival. in this study, we evaluated the outcomes of renal transplantation from cadaver, related donors and unrelated donors in isfahan. methods we evaluated all of the patients who underwent ...

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A comparison between allogeneic stem cell transplantation from unmanipulated haploidentical and unrelated donors in acute leukemia

BACKGROUND In the absence of a HLA-matched related or matched unrelated donor, allogeneic stem cell transplantation (allo-SCT) from mismatched unrelated donors or haploidentical donors are potential alternatives for patients with acute leukemia with an indication to allo-SCT. The objective of this study was to compare the outcome of allo-SCT from T cell-replete haploidentical (Haplo) versus mat...

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Reduced-Intensity Transplantation for Lymphomas Using Haploidentical Related Donors Versus HLA-Matched Sibling Donors: A Center for International Blood and Marrow Transplant Research Analysis.

PURPOSE Related donor haploidentical hematopoietic cell transplantation (Haplo-HCT) using post-transplantation cyclophosphamide (PT-Cy) is increasingly used in patients lacking HLA-matched sibling donors (MSD). We compared outcomes after Haplo-HCT using PT-Cy with MSD-HCT in patients with lymphoma, using the Center for International Blood and Marrow Transplant Research registry. MATERIALS AND...

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Although some trials have allowed matched or single human leukocyte antigen (HLA)-mismatched related donors (mmRDs) along with HLA-matched sibling donors (MSDs) for pediatric bone marrow transplantation in early-stage hematologic malignancies, whether mmRD grafts lead to similar outcomes is not known. We compared patients < 18 years old reported to the Center for International Blood and Marrow ...

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ژورنال

عنوان ژورنال: Blood Advances

سال: 2017

ISSN: 2473-9529,2473-9537

DOI: 10.1182/bloodadvances.2016002196